| Characteristic | Details |
|---|---|
| Generic Name | Metformin HCl and Sitagliptin |
| Dosage Forms | 50/500 mg, 50/1000 mg, 100/1000 mg |
| Therapeutic Class | Antidiabetic Agent |
| Administration Route | Oral |
| Visit Janumet Site | |
Janumet combines Metformin and Sitagliptin. Metformin decreases hepatic glucose production. It enhances insulin sensitivity. Sitagliptin inhibits the enzyme DPP-4. This increases incretin levels. Incretins are hormones. They regulate glucose homeostasis.
Janumet is a well-established option. It targets type 2 diabetes management. This combination offers multifaceted benefits. It addresses hyperglycemia via multiple mechanisms. Metformin reduces glucose production in the liver. Sitagliptin prolongs the action of hormones. They stimulate insulin release in response to meals.
Patients should consult their healthcare provider. It is crucial before initiating Janumet therapy. Dosing adjustments may be necessary. They depend on renal function and other medical conditions. Regular monitoring of blood glucose levels is essential. This ensures optimal control.
Janumet should be administered with meals. This minimizes gastrointestinal side effects. The dosage of Janumet 50/500 mg is twice daily. The physician determines the dosing schedule. This is based on the patient’s glycemic control.
Patients must follow prescribed instructions. They should never exceed the recommended dose. Consistency in administration time enhances effectiveness. Missing doses can compromise glucose management.
Adherence to dietary guidelines is critical. Exercise complements Janumet’s action. Together, they optimize glucose control. Regular follow-up appointments help assess therapy progress.
In cases of missed doses, patients should take the dose as soon as remembered. They should skip if the next scheduled dose is near. Double dosing should be avoided. This reduces the risk of hypoglycemia.
Janumet has specific contraindications. These include hypersensitivity to any component. Severe renal impairment prohibits use. Metabolic acidosis, including diabetic ketoacidosis, is another contraindication.
Patients with liver disease must exercise caution. Alcohol abuse can potentiate the effects of metformin. This leads to increased risk of lactic acidosis. Consultation with a healthcare provider is necessary in such scenarios.
Pregnancy and breastfeeding require careful consideration. The physician evaluates the risk-benefit ratio. Adequate contraceptive measures should be in place for women of childbearing age.
Prior to initiation, a thorough medical history is crucial. This aids in identifying potential contraindications. It ensures patient safety and drug efficacy.
Proper storage conditions preserve Janumet’s efficacy. Store at room temperature, 20-25°C (68-77°F). Avoid excess heat and moisture. Keep the medication in its original container.
Ensure the container is tightly closed. This protects against contamination. Direct sunlight exposure should be avoided. This prevents degradation of active components.
Janumet must be kept out of reach of children. Accidental ingestion could be harmful. Do not use after the expiration date. Disposal of expired medication should follow local regulations.
Proper storage extends the shelf life of Janumet. It maintains the stability of metformin and sitagliptin.
Gastrointestinal symptoms are common. These include nausea and diarrhea. Taking Janumet with meals reduces these effects. Gradual dose escalation can also help.
Lactic acidosis is a rare but serious side effect. Recognizing early symptoms is crucial. They include muscle pain and respiratory distress. Immediate medical attention is necessary.
Monitoring blood glucose levels can identify hypoglycemia. Symptoms include dizziness and sweating. Adjustments in diet or medication may be needed. Patients should carry a source of fast-acting glucose.
Janumet is not available over the counter. It requires a prescription. This ensures appropriate medical supervision. Self-medication can lead to complications.
Physicians evaluate patient history and health status. They determine the suitability of Janumet. This includes assessing potential drug interactions.
Regular follow-ups facilitate dose adjustments. They help in managing side effects. Physicians provide guidance on lifestyle modifications.
For comprehensive information, access reliable sources. For instance, the National Center for Biotechnology Information offers scientific articles. This ensures informed decision-making.
Se ha recibido un incentivo de la Agencia de Innovación y Desarrollo de y Desarrollo de Andalucía IDEA, de la Junta de Andalucía, por un importe de 8.498,88 €, cofinanciado en un 80% por la Unión Europea a través del Fondo Europeo de Desarrollo Regional, FEDER para la realización del proyecto Proyecto para planificación, desarrollo y ejecución de plan de marketing digital con el objetivo de Garantizar un mejor uso de las tecnologías de la información.
